Neglected Patients Neglected diseases continue to cause significant morbidity and mortality in the developing world. Yet, of the 850 new therapeutic products approved between 2000 and 2011, only 4% (and only 1% of all approved NCEs) were indicated for neglected diseases, even though these diseases account for 11% of the global disease burden. Sleeping Sickness Sleeping sickness is endemic in 36 African countries. 13 million people are at medium to high risk of being infected. Leishmaniasis Leishmaniasis occurs in 98 countries with 350 million people at risk worldwide. Chagas Disease Chagas disease is endemic in 21 countries across Latin America and kills more people in the region than malaria. Paediatric HIV 2.6 million children below 15 years of age are living with HIV globally, mainly in sub-Saharan Africa, and 410 of them die every day Filarial Diseases 37 million people are infected with onchocerciasis (river blindness). Mycetoma Stigmatizing disease that causes devastating deformities, often resulting in amputation and morbidity. Treatment success is less than 35%. Hepatitis C 130-150 million people are living with chronic infection, of which 85% live in low- and middle-income countries.
